L-亮氨酸 |
| 时间：2023-07-15 来源：化工号 作者：C6H13NO2 |
亮氨酸L-亮氨酸L-白氨酸氨基异己酸L-闪白氨基酸A一氨基异己酸亮氨酸 (LEU)亮氨酸溶液 (LEU)2-氨基-4-甲基戊酸L-2-氨基-4-甲基戊酸(S)-2-氨基-4-甲基戊酸亮氨酸 (LEU)溶液,100PPML-白氨酸,L-闪白氨基酸,氨基异己酸
| 中文名 | L-亮氨酸
| | 英文名 | L-Leucine
| | 别名 | 亮氨酸
L-亮氨酸
L-白氨酸
氨基异己酸
L-闪白氨基酸
A一氨基异己酸
亮氨酸 (LEU)
亮氨酸溶液 (LEU)
2-氨基-4-甲基戊酸
L-2-氨基-4-甲基戊酸
(S)-2-氨基-4-甲基戊酸
亮氨酸 (LEU)溶液,100PPM
L-白氨酸,L-闪白氨基酸,氨基异己酸
| | 英文别名 | L-Leu
Leucine
H-Leu-OH
L-Leucine
1-Leucine
L(+)LEUCINE
4-methyl-norvalin
4-methyl-l-norvalin
2-amino-4-methyl-valericaci
2-amino-4-methylpentanoicacid
2-Amino-4-methylpentanoic acid
(s)-2-amino-4-methylvalericacid
(S)-2-Amino-4-methylpentanoic acid
alpha-Amino-gamma-methylvaleric acid
| | CAS | 61-90-5
200936-87-4
| | EINECS | 200-522-0 | | 化学式 | C6H13NO2
| | 分子量 | 131.17 | | InChI | InChI=1/C6H13NO2/c1-4(2)3-5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)/t5-/m0/s1 | | 密度 | 1,293 g/cm3 | | 熔点 | >300 °C (lit.) | | 沸点 | 122-134 °C(Press: 2-3 Torr) | | 比旋光度 | 15.4 º (c=4, 6N HCl) | | 闪点 | 145-148°C | | 水溶性 | 22.4 g/L (20 C) | | 蒸汽压 | <1 hPa (20 °C) | | JECFA Number | 1423 | | 溶解度 | 1 M HCl: 50mg/mL | | 折射率 | 1.4630 (estimate) | | 酸度系数 | 2.328(at 25℃) | | PH值 | 5.5-6.5 (20g/l, H2O, 20℃) | | 存储条件 | 2-8°C | | 稳定性 | Stability Moisture and light sensitive. Incompatible with strong oxidising agents. | | 外观 | powder | | 颜色 | White to Off-white | | 最大波长(λmax) | ['λ: 260 nm Amax: 0.05',
, 'λ: 280 nm Amax: 0.05'] | | Merck | 14,5451 | | BRN | 1721722 | | 物化性质 | 白色有光泽六面体晶体或白色结晶性粉末。略有苦味(DL-亮氨酸呈甜味)。于145～148℃升华。熔点293~295℃(分解)。在烃类存在下，在无机酸水溶液中性能稳定。每g溶于约40ml水和约100ml醋酸。微溶于乙醇(0.07%)，溶于稀盐酸和碱性氢氧化物和碳酸盐溶液。不溶于乙醚。属必需氨基酸，成人男子需要量2.2g/d(151本)。为婴儿正常生长及成人维持正常氮平衡所必需。天然品存在于脾脏、心脏等中，并以蛋白质形式存在于各种动植物组织中，腐败分解后可游离而出。 | | 产品用途 | 用作医药原料及食品添加剂 | | MDL号 | MFCD00002617 | | 安全术语 | 24/25 - 避免与皮肤和眼睛接触。
| | WGK Germany | 3 | | RTECS | OH2850000 | | TSCA | Yes | | 海关编号 | 29224995 | | 上游原料 | 邻二甲苯 硫酸 碳酸氢铵 | | 下游产品 | L-苯丙氨酸 N-乙酰-L-亮氨酸 | | 参考资料 展开查看 | 1. 金顺顺 姚康 印遇龙 等. 亮氨酸和α-酮戊二酸对小鼠体重 血清及脏器的影响[J]. 食品与机械 2019 035(008):172-176.
2. 罗艳华, 王全杰, 陈沛海,等. 蛋白水解物水解度测定方法的研究[J]. 皮革与化工, 2017, 02:32-37.
3. 罗艳华 王全杰 陈沛海. CaO NaOH对铬革屑水解效果的对比[J]. 皮革与化工 2017 034(003):1-12.
4. 陈发忠, 廖东庆, 李晓明,等. 米曲霉AS3.800基因工程转化体系的构建[J]. 轻工科技, 2013(06):12-15.
5. 侯丽娟 严超 齐晓茹 王颉. 不同品种红枣酿制枣酒的香气差异性研究[J]. 食品工业 2017(5):208-212.
6. 严超, 侯丽娟, 齐晓茹,等. 红枣白兰地发酵过程中酒醅氨基酸和有机酸的变化分析[J]. 食品工业科技, 2017, 38(014):121-125.
7. 李婉斯, 李婷, 陆春怡,等. 基于HPLC指纹图谱及聚类分析评价市售阿胶的质量[J]. 上海中医药大学学报, 2017, 031(006):91-96.
8. 王婷婷,郜玉钢,臧埔,赵岩,何忠梅,祝洪艳,张连学.复方麦鹿芪人参制剂主要成分变化及其在肝癌H22荷瘤小鼠体内的抗肿瘤作用[J].吉林大学学报(医学版),2017,43(04):698-704+858-859.
9. 谈梦霞, 陈佳丽, 邹立思,等. 不同贮藏条件对麦冬药材质量的影响[J]. 中药材, 2018(11).
10. Li, Suhong, et al. "Mechanisms of high concentration valine-mediated inhibition of peach tree shoot growth." Frontiers in Plant Science 11 (2020).https://dx.doi.org/10.3389%2Ffpls.2020.603067
11. Zhongqian Song, Fengyu Quan, Yuanhong Xu, Mengli Liu, Liang Cui, Jingquan Liu, Multifunctional N,S co-doped carbon quantum dots with pH- and thermo-dependent switchable fluorescent properties and highly selective detection of glutathione, Carbon, Volume 10
12. Qu, Fei, et al. "Fluorescent Detection of 2, 4-Dichlorophenoxyacetic Acid in Food Samples Based on Covalent Organic Frameworks and MnO 2 Nanosheets." Food Analytical Methods 13.10 (2020): 1842-1851.https://doi.org/10.1007/s12161-020-01807-2
13. Wang, Chengcheng, et al. "Distribution patterns for metabolites in medicinal parts of wild and cultivated licorice." Journal of pharmaceutical and biomedical analysis 161 (2018): 464-473.https://doi.org/10.1016/j.jpba.2018.09.004
14. Zhao, Zheng, et al. "Cholinium amino acids-glycerol mixtures: New class of solvents for pretreating wheat straw to facilitate enzymatic hydrolysis." Bioresource technology 245 (2017): 625-632.https://doi.org/10.1016/j.biortech.2017.08.209
15. [IF=9.594] Zhongqian Song et al."Multifunctional N,S co-doped carbon quantum dots with pH- and thermo-dependent switchable fluorescent properties and highly selective detection of glutathione."Carbon. 2016 Aug;104:169
16. [IF=6.079] Tian Luo et al."Determination of underivatized amino acids to evaluate quality of beer by capillary electrophoresis with online sweeping technique."J Food Drug Anal. 2017 Oct;25:789
17. [IF=5.923] Cuihua Chen et al."Variations in Physiology and Multiple Bioactive Constituents under Salt Stress Provide Insight into the Quality Evaluation of Apocyni Veneti Folium."Int J Mol Sci. 2018 Oct;19(10):3042
18. [IF=4.952] Fengfeng Qu et al."Effect of different drying methods on the sensory quality and chemical components of black tea."Lwt Food Sci Technol. 2019 Jan;99:112
19. [IF=4.411] Yujiao Hua et al."Quality Evaluation of Pseudostellariae Radix Based on Simultaneous Determination of Multiple Bioactive Components Combined with Grey Relational Analysis."Molecules. 2017 Jan;22(1):13
20. [IF=4.098] Chunlin Li et al."Rapid and non-destructive discrimination of special-grade flat green tea using Near-infrared spectroscopy."Spectrochim Acta A. 2019 Jan;206:254
21. [IF=3.535] Tian Luo et al."Establishing a sensitive capillary electrophoresis-UV method for direct determination of amino acids to evaluate vinegar quality."Electrophoresis. 2018 Jun;39(11):1410-1416
22. [IF=2.896] Jing Ke et al."Development of a gradient micellar liquid chromatographic method eluting from micellar mode to high submicellar mode for the rapid separation of free amino acids."Anal Methods-Uk. 2017 Mar;9(11):1762-1770
23. [IF=2.896] Ya-yun Chen et al."Determination of free amino acids and nucleosides and nucleobases in Annona squamosa L. fruitages from different regions in China by LC-QTRAP-MS/MS."Anal Methods-Uk. 2017 Jun;9(25):3862-3869
24. [IF=2.727] Tian Luo et al."Quality assessment of soy sauce using underivatized amino acids by capillary electrophoresis."International Journal Of Food Properties. 2018 Jan 08
25. [IF=1.913] Xie Yunfei et al."Rapid Determination of Amino Acids in Beer, Red Wine, and Donkey-Hide Gelatin by Gradient Elution of HPLC: From Micellar Liquid Chromatography to High Submicellar Liquid Chromatography."J Aoac Int. 2018 Jan;101(1):249-255
26. [IF=5.537] Yurong Ma et al."Pre-cut NaCl solution treatment effectively inhibited the browning of fresh-cut potato by influencing polyphenol oxidase activity and several free amino acids contents."Postharvest Biol Tec. 2021 Aug;178:111543
27. [IF=4.952] Huan Zhang et al."Label-free quantification proteomics reveals the active peptides from protein degradation during anaerobic fermentation of tea."Lwt Food Sci Technol. 2021 Oct;150:111950
28. [IF=4.821] Peng Wan et al."Analysis of aroma-active compounds in bighead carp head soup and their influence on umami of a model soup."Microchem J. 2021 Sep;168:106436
29. [IF=4.556] Dandan Zhao et al."Physico-chemical properties and free amino acids profiles of six wolfberry cultivars in Zhongning."J Food Compos Anal. 2020 May;88:103460
30. [IF=4.411] Mengxia Tan et al."Quality Evaluation of Ophiopogonis Radix from Two Different Producing Areas."Molecules. 2019 Jan;24(18):3220
31. [IF=4.411] Shengxin Yin et al."Comparison of Multiple Bioactive Constituents in the Corolla and Other Parts of Abelmoschus manihot."Molecules. 2021 Jan;26(7):1864
32. [IF=4.379] Feng Lin et al."Chemical profile changes during pile fermentation of Qingzhuan tea affect inhibition of α-amylase and lipase."Sci Rep-Uk. 2020 Feb;10(1):1-10
33. [IF=4.36] Zhao-Yi Wang et al."Integrated strategy of LC-MS and network pharmacology for predicting active constituents and pharmacological mechanisms of Ranunculus japonicus Thunb. for treating rheumatoid arthritis."J Ethnopharmacol. 2021 May;271:113818
34. [IF=4.35] Xiaomei Dai et al."1-Methylcyclopropene Preserves the Quality of Chive (Allium schoenoprasum L.) by Enhancing Its Antioxidant Capacities and Organosulfur Profile during Storage."Foods. 2021 Aug;10(8):1792
35. [IF=4.142] Wang Chenxi et al."Systematic quality evaluation of Peiyuan Tongnao capsule by offline two-dimensional liquid chromatography/quadrupole-Orbitrap mass spectrometry and adjusted parallel reaction monitoring of quality markers."Anal Bioanal Chem. 2019 Nov;4
36. [IF=3.935] Biru Shi et al."Investigation on the stability in plant metabolomics with a special focus on freeze-thaw cycles: LC–MS and NMR analysis to Cassiae Semen (Cassia obtusifolia L.) seeds as a case study."J Pharmaceut Biomed. 2021 Sep;204:114243
37. [IF=3.361] Ning Zhao et al."Ratiometric fluorescence probe of Cu2+ and biothiols by using carbon dots and copper nanoclusters."Rsc Adv. 2021 Oct;11(53):33662-33674
38. [IF=3.361] Furong Wang et al."Effect of free amino acids and peptide hydrolysates from sunflower seed protein on the formation of pyrazines under different heating conditions."Rsc Adv. 2021 Aug;11(45):27772-27781
39. [IF=3.24] Zhichen Cai et al."Metabolomics characterizes the metabolic changes of Lonicerae Japonicae Flos under different salt stresses."Plos One. 2020 Dec;15(12):e0243111
40. [IF=2.849] Peng Lu et al."Physicochemical and Pharmacokinetic Evaluation of Spray-Dried Coformulation of Salvia miltiorrhiza Polyphenolic Acid and L-Leucine with Improved Bioavailability."J Aerosol Med Pulm D. 2020 Apr;33(2):73-82
41. [IF=2.097] Ke Jing et al."Isocratic micellar liquid chromatography using mixed anionic and non-ionic surfactants as mobile phase additives for separation of 17 free amino acids."Chem Pap. 2019 Oct;73(10):2417-2426
42. [IF=2.043] Guan Chengran et al."Variation of bitter components of the asparagus juices during lactic acid bacteria fermentation."Biosci Biotech Bioch. 2021 Oct;85(11):2300-2310
43. [IF=1.618] Wang Shengnan et al."Simultaneous Determination of Iridoid Glycosides, Phenylpropanoid Glycosides, Organic Acids, Nucleosides and Amino Acids in Scrophulariae Radix Processed by Different Processing Methods by HPLC-QTRAP-MS/MS."J Chromatogr Sci. 2021 Jun;
44. [IF=6.598] Peng Lu et al."Salvianolic acid B dry powder inhaler for the treatment of idiopathic pulmonary fibrosis."Asian Journal of Pharmaceutical Sciences. 2022 Apr;:
45. [IF=3.463] Xiaomei Dai et al."S-alk(en)ylcysteine sulfoxides biosynthesis and free amino acids profile in different parts of postharvest chive (Allium schoenoprasum L.)."SCIENTIA HORTICULTURAE. 2022 Sep;303:111191 |
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