85721-33-1 |
| 时间：2023-07-15 来源：化工号 作者：C17H18FN3O3 |
特美力悉复欢适普灵丙氟哌酸环丙氟哌酸
| 中文名 | 环丙沙星
| | 英文名 | Ciprofloxacin
| | 别名 | 特美力
悉复欢
适普灵
丙氟哌酸
环丙氟哌酸
| | 英文别名 | Ciprofloxacin Base
| | CAS | 85721-33-1
| | 化学式 | C17H18FN3O3
| | 分子量 | 331.34 | | InChI | InChI=1/C17H18FN3O3.ClH/c18-13-7-11-14(8-15(13)20-5-3-19-4-6-20)21(10-1-2-10)9-12(16(11)22)17(23)24;/h7-10,19H,1-6H2,(H,23,24);1H | | 熔点 | 255-257°C | | 沸点 | 581.8°C at 760 mmHg | | 闪点 | 305.6°C | | 蒸汽压 | 2.24E-14mmHg at 25°C | | 溶解度 | DMSO <1 mg/mL；Water <1 mg/mL；Ethanol <1 mg/mL。在甲醇中微溶，在乙醇中不溶 | | 存储条件 | 2-8℃ | | 外观 | 微黄色或类白色结晶粉末 | | Merck | 14,2314 | | BRN | 3568352 | | 产品用途 | 适用于呼吸道感染、泌尿道、耳鼻喉、皮肤和软组织、胃肠道感染等 | | MDL号 | MFCD00185755 | | WGK Germany | 2 | | 上游原料 | 苯乙酮 环丙胺 碳酸二甲酯 | | 下游产品 | 乳酸环丙沙星 | | 参考资料 展开查看 | 1. 白东东 李新圃 杨峰 等. 中药对奶牛乳房炎6种主要病原菌的体外抗菌活性筛选试验[J]. 中兽医医药杂志 2019 038(002):49-52.
2. 白东东 李新圃 杨峰 等. 乳黄消口服液滋阴、扶正及祛邪功效的研究[J]. 中国畜牧兽医 2019 046(005):1491-1498.
3. 白东东, 李新圃, 杨峰,等. 地肤通乳散治疗奶牛乳房炎临床疗效及作用靶点预测[J]. 浙江农业学报, 2019, 31(005):730-736.
4. 韩斯琴高娃, 孙佳, 包琳,等. 基于SERS技术检测牛奶中环丙沙星的研究[J]. 药物分析杂志, 2018, 038(005):802-805.
5. 张吉亚, 刘畅, 关雅元,等. 载药纳米磷酸钙的制备及其抗菌性能研究[J]. 化学研究与应用, 2016, 28(009):1260-1267.
6. 黄昭, 李跑, 曹亚男,等. 诺氟沙星磁分子印迹纳米粒子的制备及其富集分离[J]. 食品研究与开发, 2020(18):52-57.
7. 王艳玲, 刘俊渤, 唐珊珊,等. 恩诺沙星分子印迹纳米纤维膜的制备及性能[J]. У, 2013, 34(012):2880-2886.
8. 彭小明, 傅大放, 秦庆东. 竹炭表面改性对两种抗生素吸附性能的影响[J]. 东南大学学报(自然科学版), 2014, 44(006):1271-1277.
9. 马君, 孔德地, 韩晓红,等. 应用银溶胶膜探测水中抗生素的表面增强拉曼光谱研究[J]. 光谱学与光谱分析, 2013(10):2688-2693.
10. 李新慧, 郑权, 李静,等. 氟喹诺酮对垂直流人工湿地性能及微生物群落的影响[J]. 环境科学, 2018, 039(010):4809-4816.
11. 于璐, 刘卫华, 刘敏轩,等. 胶体金免疫层析法快速检测牛奶中环丙沙星残留[J]. 食品研究与开发, 2019, v.40;No.371(22):167-171.
12. 刘敏芳, 曹梦蕊, 李荣旭,等. 广东部分地区水禽源沙门氏菌的分离鉴定与药物敏感性分析[J]. 黑龙江畜牧兽医, 2018(10).
13. 张济培, 韦庆兰, 谭华龙,等. 水禽源大肠杆菌耐药性及β-内酰胺类和喹诺酮类耐药基因检测分析[J]. 中国预防兽医学报, 2016, 38(009):751-754.
14. 赵素华, 范红结. 皖北地区禽源大肠杆菌的血清型鉴定与耐药性分析[J]. 畜牧与兽医, 2017, 49(004):95-98.
15. 韦庆兰, 张济培, 任涛,等. 广东地区水禽源大肠杆菌药物敏感性分析[J]. 黑龙江畜牧兽医, 2015, 000(012):180-181.
16. 刘若冰,郝怡环,杨茜,焦文雅,王向红.基于核酸适配体的AccuBlue荧光法检测动物食品中的恩诺沙星[J].食品科学,2020,41(24):310-315.
17. 黄昭,李跑,曹亚男,李佳银,刘霞.诺氟沙星磁分子印迹纳米粒子的制备及其富集分离[J].食品研究与开发,2020,41(18):52-57.
18. 张政,马更勤,王宏勋,侯温甫,周敏.副溶血弧菌耐药诱导株的生物特性与多药外排泵表达[J].现代食品科技,2020,36(08):15-22.
19. 陈书鑫,王静,何士冲,刘铮铮,冯华军,穆朋倩.超高效液相色谱串联质谱法测定水体中17种抗生素[J].中国环境监测,2020,36(06):119-126.
20. Dai, Z., Liu, J., Tang, S. et al. Optimization of enrofloxacin-imprinted polymers by computer-aided design. J Mol Model 21, 290 (2015). https://doi.org/10.1007/s00894-015-2836-5
21. Guo, Hai, et al. "Highly crystalline porous carbon nitride with electron accumulation capacity: Promoting exciton dissociation and charge carrier generation for photocatalytic molecular oxygen activation." Chemical Engineering Journal 409 (2021): 128030.ht
22. [IF=3.247] Wen Huang et al."Removal of ciprofloxacin from aqueous solution by rabbit manure biochar."Environ Technol. 2020;41(11):1380-1390
23. [IF=2.596] Jing Wang et al."The development of a biomimetic enzyme-linked immunosorbent assay based on the molecular imprinting technique for the detection of enrofloxacin in animal-based food."Anal Methods-Uk. 2017 Dec;9(47):6682-6688
24. [IF=1.81] Dai Zhengqiang et al."Optimization of enrofloxacin-imprinted polymers by computer-aided design."J Mol Model. 2015 Nov;21(11):1-9
25. [IF=13.273] Hai Guo et al."Highly crystalline porous carbon nitride with electron accumulation capacity: Promoting exciton dissociation and charge carrier generation for photocatalytic molecular oxygen activation."Chem Eng J. 2021 Apr;409:128030
26. [IF=9.642] Chaofan Zheng et al."Structural design of magnetic biosorbents for the removal of ciprofloxacin from water."Bioresource Technol. 2020 Jan;296:122288
27. [IF=7.514] Yanan Cao et al."Rapid and selective extraction of norfloxacin from milk using magnetic molecular imprinting polymers nanoparticles."Food Chem. 2021 Aug;353:129464
28. [IF=2.896] Lu Yu et al."Development and application of a lateral flow colloidal gold immunoassay strip for the rapid quantification of ciprofloxacin in animal muscle."Anal Methods-Uk. 2019 Jun;11(25):3244-3251
29. [IF=2.863] Yu Zhang et al."Antibiotic residues in cattle and sheep meat and human exposure assessment in southern Xinjiang, China."Food Sci Nutr. 2021 Nov;9(11):6152-6161
30. [IF=6.498] Jingyun Shi et al."Groundwater antibiotics and microplastics in a drinking-water source area, northern China: Occurrence, spatial distribution, risk assessment, and correlation."Environ Res. 2022 Jul;210:112855
31. [IF=7.312] Yunyun Li et al."Mass transfer enhancement for rapid, selective extraction of pharmaceuticals by enlarging the microporous on isostructural zeolitic imidazolate Framework-8."SEPARATION AND PURIFICATION TECHNOLOGY. 2022 Jul;293:121102
32. [IF=2.896] Chunhui Lu et al."Rapid quantitative detection of chloramphenicol in three food products by lanthanide-labeled fluorescent-nanoparticle immunochromatographic strips."Analytical Methods. 2022 May;14(17):1705-1714 |
|
|
|
|
