L-天门冬氨酸 |
| 时间：2023-07-15 来源：化工号 作者：C4H7NO4 |
L-天冬酸L-抗坏血酸L-天冬氨酸L-天门冬氨酸L-天冬门氨酸(S)-氨基丁二酸(S)-(+)-氨基琥珀酸天冬氨酸 (ASP)溶液,100PPML-天门冬氨酸 L-ASPARTIC ACID
| 中文名 | L-天门冬氨酸
| | 英文名 | L(+)-Aspartic acid
| | 别名 | L-天冬酸
L-抗坏血酸
L-天冬氨酸
L-天门冬氨酸
L-天冬门氨酸
(S)-氨基丁二酸
(S)-(+)-氨基琥珀酸
天冬氨酸 (ASP)溶液,100PPM
L-天门冬氨酸 L-ASPARTIC ACID
| | 英文别名 | H-Asp-OH
asparagicacid
Asparagic acid
L-Aspantic acid
asparaginsaeure
L-Aspartic acid
asparaginicacid
Asparaginic acid
L-Asparaginic acid
L(+)-Aspartic acid
(s)-butanedioicaci
L-(+)-Aspartic acid
L-Aminosuccinic acid
alpha-Aminosuccinic acid
L-2-Aminobutanedioic acid
| | CAS | 56-84-8
| | EINECS | 200-291-6 | | 化学式 | C4H7NO4
| | 分子量 | 133.1 | | InChI | InChI=1/C4H7NO4/c5-2(4(8)9)1-3(6)7/h2H,1,5H2,(H,6,7)(H,8,9)/t2-/m0/s1 | | InChIKey | CKLJMWTZIZZHCS-REOHCLBHSA-N | | 密度 | 1.66 | | 熔点 | >300°C (dec.)(lit.) | | 沸点 | 245.59°C (rough estimate) | | 比旋光度 | 25 º (c=8, 6N HCl) | | 水溶性 | 5 g/L (25 ºC) | | JECFA Number | 1429 | | 溶解度 | H2O: 5mg/mL | | 折射率 | 1.4540 (estimate) | | 酸度系数 | 1.99(at 25℃) | | PH值 | 2.5-3.5 (4g/l, H2O, 20℃) | | 存储条件 | Store below +30°C. | | 稳定性 | Stable. Combustible. Incompatible with strong oxidising agents. | | 外观 | powder | | 颜色 | White | | 气味 | acid taste | | 最大波长(λmax) | ['λ: 260 nm Amax: 0.20',
, 'λ: 280 nm Amax: 0.10'] | | Merck | 14,840 | | BRN | 1723530 | | 物化性质 | 呈白色结晶或结晶性粉末，味微酸。溶于沸水，25℃时微溶于水 (0.5%)，易溶于稀酸和氢氧化钠溶液中，不溶于乙醇、乙醚、加热至270℃分解，等电点2.77，其比旋度与所溶的溶剂有关。在酸溶液中为右旋，碱溶液中为左旋，水溶液中为右旋。[α]25D+5.05 (C=0.5-2.0 g/ml, H2O)。 | | 产品用途 | 用于合成甜味剂，医药上用于治疗心脏病，用作肝功能促进剂、氨解毒剂、疲劳消除剂和氨基酸输液成分等 | | MDL号 | MFCD00002616 | | 危险品标志 | Xi - 刺激性物品
Xn - 有害物品
| | 风险术语 | R36 - 刺激眼睛。
R36/37/38 - 刺激眼睛、呼吸系统和皮肤。
R20/21/22 - 吸入、皮肤接触及吞食有害。
| | 安全术语 | S26 - 不慎与眼睛接触后，请立即用大量清水冲洗并征求医生意见。
S24/25 - 避免与皮肤和眼睛接触。
S22 - 切勿吸入粉尘。
S36 - 穿戴适当的防护服。
| | WGK Germany | 2 | | RTECS | CI9098500 | | FLUKA BRAND F CODES | 10 | | TSCA | Yes | | 海关编号 | 29224995 | | Hazard Class | IRRITANT | | 上游原料 | 氨水 反丁烯二酸 碳 硫酸 液氨 | | 下游产品 | L-丙氨酸 DL-天门冬氨酸 L-天门冬氨酸钙 | | 参考资料 展开查看 | 1. 王淑娜 康少鑫 张玉玲 等. 共聚物PAMA在CaCO3饱和溶液中的络合性能研究[J]. 高校化学工程学报 2018 032(001):168-175.
2. 张冰如,胡伟,李风亭.固体酸式催化剂催化合成聚天冬氨酸的研究[J].工业水处理,2012,32(05):76-78.
3. 张玉玲, 李伟, 李旭东,等. 天冬氨酸-柠檬酸共聚物对碳酸钙的抑制性能[J]. 精细化工, 2018(11):1877-1884.
4. 李志强, 杜盼盼, 武慧欣,等. 孕鼠常见微波暴露对仔鼠行为发育及认知的影响[J]. 环境与职业医学, 2018, 035(005):438-442.
5. 王小琴, 邹玉安, 薛茜,等. 缺血预处理对大鼠脑组织及血清氨基酸水平的影响[J]. 山东医药, 2016, 56(010):31-32.
6. 王小琴, 邹玉安, 郭春燕,等. 脑缺血预处理对大鼠脑组织中氨基酸及肿瘤坏死因子－α含量的影响[J]. 中国临床药理学杂志, 2016, 32(005):424-426.
7. 梁浩明, 龙晓英, 卢耀文,等. 鼻吸入薄荷油对小鼠精神疲劳行为及脑内氨基酸类神经递质的影响[J]. 中药新药与临床药理, 2015(05):649-654.
8. 邹兰, 胡月英, 陈文学. 黑胡椒提取物对枯草芽孢杆菌生理代谢的影响[J]. 食品工业科技, 2015, 36(023):148-151.
9. 邹兰, 胡月英, 陈文学. 黑胡椒石油醚相提取物对大肠杆菌和金黄色葡萄球菌的抑菌机制研究[J]. 食品科技, 2018(6).
10. 谈梦霞, 陈佳丽, 邹立思,等. 不同贮藏条件对麦冬药材质量的影响[J]. 中药材, 2018(11).
11. 王婷婷,郜玉钢,臧埔,赵岩,何忠梅,祝洪艳,张连学.复方麦鹿芪人参制剂主要成分变化及其在肝癌H22荷瘤小鼠体内的抗肿瘤作用[J].吉林大学学报(医学版),2017,43(04):698-704+858-859.
12. 侯丽娟 严超 齐晓茹 王颉. 不同品种红枣酿制枣酒的香气差异性研究[J]. 食品工业 2017(5):208-212.
13. 李婉斯, 李婷, 陆春怡,等. 基于HPLC指纹图谱及聚类分析评价市售阿胶的质量[J]. 上海中医药大学学报, 2017, 031(006):91-96.
14. 马长中, 罗章, 辜雪冬. 林芝砖红绒盖牛肝菌的营养成分分析及评价[J]. 食品科学, 2016, 37(024):124-129.
15. 马桂芝,陈雪珊,蒋思思,段霞.柱前衍生HPLC-UV法测定类风湿性关节炎大鼠尿样中16种氨基酸含量[J].新疆医科大学学报,2018,41(08):1001-1005.
16. 甘学文,王光耀,邓仕彬,张春晖,崔和平,刘曙光,于静洋,成涛,张晓鸣.美拉德反应中间体对卷烟评吸品质的影响及其风味受控形成研究[J].食品与机械,2017,33(06):46-52.
17. 严超, 侯丽娟, 齐晓茹,等. 红枣白兰地发酵过程中酒醅氨基酸和有机酸的变化分析[J]. 食品工业科技, 2017, 38(014):121-125.
18. 祝洪艳, 张荻, 张力娜,等. 柱前衍生化HPLC法检测紫苏子和紫苏叶中氨基酸的含量[J]. 药物分析杂志, 2017(10):1858-1864.
19. 唐何娜, 杨磊, 欧阳志远,等. 基于体外仿生的海水珍珠矿化机制初步研究[J]. 电子显微学报, 2017, 036(006):589-597.
20. 孔艳,邢雪,李娜,于巧红,王萌,刘志东.注射用血栓通（冻干）与3种生物化学注射剂配伍稳定性研究[J].药物评价研究,2020,43(10):1988-1996
21. 王蓉蓉,胡争艳,吴平谷,单乐天,黄家卫,王春雷.超高效液相-串联质谱分析法同时测定蕲蛇提取物中核苷及氨基酸的含量[J].中国卫生检验杂志,2020,30(15):1793-1797+1803.
22. 杨挡,封亮,刘俊,赵菁,李超,朱法根,邵建国,贾晓斌,孙娥.基于物料性质表征技术的蒲地蓝消炎口服液儿童用药顺应性改善研究[J].世界中医药,2020,15(15):2221-2227.
23. Wang, Chengcheng, et al. "Distribution patterns for metabolites in medicinal parts of wild and cultivated licorice." Journal of pharmaceutical and biomedical analysis 161 (2018): 464-473.https://doi.org/10.1016/j.jpba.2018.09.004
24. Niu, Fushuang, et al. "Controllable electrochemical/electroanalytical approach to generate nitrogen-doped carbon quantum dots from varied amino acids: pinpointing the utmost quantum yield and the versatile photoluminescent and electrochemiluminescent appli
25. Sun, Xiaoshu, et al. "Anti-convulsant effects of cultures bear bile powder in febrile seizure via regulation of neurotransmission and inhibition of neuroinflammation." Journal of Ethnopharmacology 262 (2020): 112998.https://doi.org/10.1016/j.jep.2020.11299
26. Chen, J., Wang, Y., Wei, X. et al. A composite prepared from MnO2 nanosheets and a deep eutectic solvent as an oxidase mimic for the colorimetric determination of DNA. Microchim Acta 187, 7 (2020). https://doi.org/10.1007/s00604-019-4021-5
27. Zhongqian Song, Fengyu Quan, Yuanhong Xu, Mengli Liu, Liang Cui, Jingquan Liu, Multifunctional N,S co-doped carbon quantum dots with pH- and thermo-dependent switchable fluorescent properties and highly selective detection of glutathione, Carbon, Volume 10
28. Zhao, Zheng, et al. "Cholinium amino acids-glycerol mixtures: New class of solvents for pretreating wheat straw to facilitate enzymatic hydrolysis." Bioresource technology 245 (2017): 625-632.https://doi.org/10.1016/j.biortech.2017.08.209
29. [IF=9.594] Zhongqian Song et al."Multifunctional N,S co-doped carbon quantum dots with pH- and thermo-dependent switchable fluorescent properties and highly selective detection of glutathione."Carbon. 2016 Aug;104:169
30. [IF=9.594] Fushuang Niu et al."Electrochemically generated green-fluorescent N-doped carbon quantum dots for facile monitoring alkaline phosphatase activity based on the Fe3+-mediating ON-OFF-ON-OFF fluorescence principle."Carbon. 2018 Feb;127:340
31. [IF=6.079] Tian Luo et al."Determination of underivatized amino acids to evaluate quality of beer by capillary electrophoresis with online sweeping technique."J Food Drug Anal. 2017 Oct;25:789
32. [IF=4.952] Fengfeng Qu et al."Effect of different drying methods on the sensory quality and chemical components of black tea."Lwt Food Sci Technol. 2019 Jan;99:112
33. [IF=4.411] Yujiao Hua et al."Quality Evaluation of Pseudostellariae Radix Based on Simultaneous Determination of Multiple Bioactive Components Combined with Grey Relational Analysis."Molecules. 2017 Jan;22(1):13
34. [IF=4.098] Chunlin Li et al."Rapid and non-destructive discrimination of special-grade flat green tea using Near-infrared spectroscopy."Spectrochim Acta A. 2019 Jan;206:254
35. [IF=3.535] Tian Luo et al."Establishing a sensitive capillary electrophoresis-UV method for direct determination of amino acids to evaluate vinegar quality."Electrophoresis. 2018 Jun;39(11):1410-1416
36. [IF=2.896] Ya-yun Chen et al."Determination of free amino acids and nucleosides and nucleobases in Annona squamosa L. fruitages from different regions in China by LC-QTRAP-MS/MS."Anal Methods-Uk. 2017 Jun;9(25):3862-3869
37. [IF=2.727] Tian Luo et al."Quality assessment of soy sauce using underivatized amino acids by capillary electrophoresis."International Journal Of Food Properties. 2018 Jan 08
38. [IF=7.79] Ye Lu et al."Enhancing hydrogel-based long-lasting chemiluminescence by a platinum-metal organic framework and its application in array detection of pesticides and D-amino acids."Nanoscale. 2020 Feb;12(8):4959-4967
39. [IF=7.46] Pengli Gao et al."Chiral carbon dots-based nanosensors for Sn(II) detection and lysine enantiomers recognition."Sensor Actuat B-Chem. 2020 Sep;319:128265
40. [IF=5.537] Yurong Ma et al."Pre-cut NaCl solution treatment effectively inhibited the browning of fresh-cut potato by influencing polyphenol oxidase activity and several free amino acids contents."Postharvest Biol Tec. 2021 Aug;178:111543
41. [IF=4.821] Peng Wan et al."Analysis of aroma-active compounds in bighead carp head soup and their influence on umami of a model soup."Microchem J. 2021 Sep;168:106436
42. [IF=4.556] Dandan Zhao et al."Physico-chemical properties and free amino acids profiles of six wolfberry cultivars in Zhongning."J Food Compos Anal. 2020 May;88:103460
43. [IF=4.411] Mengxia Tan et al."Quality Evaluation of Ophiopogonis Radix from Two Different Producing Areas."Molecules. 2019 Jan;24(18):3220
44. [IF=4.379] Feng Lin et al."Chemical profile changes during pile fermentation of Qingzhuan tea affect inhibition of α-amylase and lipase."Sci Rep-Uk. 2020 Feb;10(1):1-10
45. [IF=4.35] Xiaomei Dai et al."1-Methylcyclopropene Preserves the Quality of Chive (Allium schoenoprasum L.) by Enhancing Its Antioxidant Capacities and Organosulfur Profile during Storage."Foods. 2021 Aug;10(8):1792
46. [IF=4.27] Cuihua Chen et al."Metabolomics characterizes metabolic changes of Apocyni Veneti Folium in response to salt stress."Plant Physiol Bioch. 2019 Nov;144:187
47. [IF=4.098] Chunlin Li et al."Discrimination of white teas produced from fresh leaves with different maturity by near-infrared spectroscopy."Spectrochim Acta A. 2020 Feb;227:117697
48. [IF=4.098] Wei Wang et al."Colorimetry and SERS dual-mode sensing of serotonin based on functionalized gold nanoparticles."Spectrochim Acta A. 2021 Nov;261:120057
49. [IF=3.935] Biru Shi et al."Investigation on the stability in plant metabolomics with a special focus on freeze-thaw cycles: LC–MS and NMR analysis to Cassiae Semen (Cassia obtusifolia L.) seeds as a case study."J Pharmaceut Biomed. 2021 Sep;204:114243
50. [IF=1.618] Wang Shengnan et al."Simultaneous Determination of Iridoid Glycosides, Phenylpropanoid Glycosides, Organic Acids, Nucleosides and Amino Acids in Scrophulariae Radix Processed by Different Processing Methods by HPLC-QTRAP-MS/MS."J Chromatogr Sci. 2021 Jun;
51. [IF=4.821] Chun-Yan Zhang et al.Investigation on the peroxidase-mimic activity of adenine phosphate and its applications.Microchem J. 2022 Feb;173:106992
52. [IF=5.833] Yin Shi-Jun et al.Preparation of yolk-shell structure NH2-MIL-125 magnetic nanoparticles for the selective extraction of nucleotides.Microchim Acta. 2021 Dec;188(12):1-13
53. [IF=4.242] Hang Yang et al."Dietary leucine requirement of juvenile largemouth bass (Micropterus salmoides) based on growth, nutrient utilization and growth-related gene analyses."Aquaculture. 2022 Jun;555:738207
54. [IF=4.539] Li-Jing Peng et al."Study on the peroxidase-like activity of cobalt phosphate and its application in colorimetric detection of hydrogen peroxide."COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS. 2022 Aug;647:129031
55. [IF=3.463] Xiaomei Dai et al."S-alk(en)ylcysteine sulfoxides biosynthesis and free amino acids profile in different parts of postharvest chive (Allium schoenoprasum L.)."SCIENTIA HORTICULTURAE. 2022 Sep;303:111191 |
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