1255942-08-5 |
| 时间：2023-07-15 来源：化工号 作者：C29H37N3O6 |
| 中文名 | DBCO-五聚乙二醇-氨基
| | 英文名 | DBCO-PEG4-NH2
| | 别名 | DBCO-五聚乙二醇-氨基
氮杂二苯并环辛炔四聚乙二醇乙胺
氮杂二苯并环辛炔-PEG4 胺
| | 英文别名 | DBCO-PEG4-NH2
DBCO-PEG4-amine
DBCO-NHCOPEG4-amine
DBCO-NH-PEG4-CH2CH2NH2
DBCO-NHCO-PEG4-amine TFA salt
Azadibenzocyclooctyne-PEG4-amine
DBCO-PEG4 amine(ADIBO-PEG4-amine)
3-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]-N-[3-(2-azatricyclo[10.4.0.04,9]hexadeca-1(16),4,6,8,12,14-hexaen-10-yn-2-yl)-3-oxopropyl]propanamide
| | CAS | 1255942-08-5
| | 化学式 | C29H37N3O6
| | 分子量 | 523.62 | | 密度 | 1.23±0.1 g/cm3(Predicted) | | 沸点 | 784.1±60.0 °C(Predicted) | | 水溶性 | Soluble in water. | | 溶解度 | Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) | | 酸度系数 | 15.14±0.46(Predicted) | | 存储条件 | -20°C Freezer, Under inert atmosphere | | 外观 | Solid | | 颜色 | Yellow to Dark Yellow Sticky | | 体外研究 | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. |
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