奥泽沙星 |
| 时间：2023-07-15 来源：化工号 作者：C21H21N3O3 |
奥泽沙星奥森沙星奥泽沙星杂质奥泽沙星杂质11-环丙基-8-甲基-7-(5-甲基-6-(甲基氨基)吡啶-3-基)-4-氧代-1,4-二氢喹啉-3-羧酸
| 中文名 | 奥泽沙星
| | 英文名 | Ozenoxacin
| | 别名 | 奥泽沙星
奥森沙星
奥泽沙星杂质
奥泽沙星杂质1
1-环丙基-8-甲基-7-(5-甲基-6-(甲基氨基)吡啶-3-基)-4-氧代-1,4-二氢喹啉-3-羧酸
| | 英文别名 | T 3912
Ozenoxacin
Ozenoxacin(T 3912)
Ozenoxacin Impurity 1
organic materials Ozenoxacin
Ozenoxacin , T 3912,UNII-V0LH498RFO
1-cyclopropyl-8-methyl-7-[5-methyl-6-(methylamino)pyridin-3-yl]-4-oxoquinoline-3-carboxylic acid
| | CAS | 245765-41-7
| | EINECS | 105-745-2 | | 化学式 | C21H21N3O3
| | 分子量 | 363.41 | | 密度 | 1.372±0.06 g/cm3(Predicted) | | 熔点 | >255°C (dec.) | | 沸点 | 573.5±50.0 °C(Predicted) | | 溶解度 | DMSO (Slightly) | | 酸度系数 | 6.46±0.50(Predicted) | | 存储条件 | 2-8°C(protect from light) | | 外观 | Solid | | 颜色 | Off-White | | 体外研究 | Ozenoxacin (OZN) shows potent antibacterial activities against clinical isolates of Gram-positive microorganisms, with MICs ranging from 0.008 to 4 mg/L. Ozenoxacin shows good activities against strains of MRSA, MSSA, MSSE, and MRSE with 2, 3, or 4 mutations in the gyrA and grlA (parC) genes. Ozenoxacin inhibits MSSA strains and S. agalactiae strains, with the rates of resistance of >10 −10 and 5.3 × 10 −10 , respectively. The maximum MIC value for mutant strains is 8 mg/L for ozenoxacin. |
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- 2-甲氧基苯氧基乙胺
- 2,4-二氟苯甲醛
- 2,4,5-三氟甲苯
- 4-乙氧基-2-氟苯甲酸
- (4R,4AS,6S,7R,7AS)-六氢-6-羟基-4-(羟基甲基)-7-甲基环戊并[C]吡喃-3(1H)-酮
- (3R,5S)-REL-1-(4-羟基-3,5-二甲氧基苯基)-7-(4-羟基苯基)-3,5-庚二醇
- 白杨素
- 6-氯-N-甲基吡啶-2-胺
- 8-羟基毛地黄毒素
- 1-乙炔基-3-氟苯
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