脱氧胆酸钠 |
| 时间：2023-07-18 来源：化工号 作者：C24H41NaO4 |
| 中文名 | 脱氧胆酸钠
| | 英文名 | sodium 3-α,12-α-dihydroxy-5-β-cholan-24-oate
| | 别名 | 脱氧胆酸钠
去氧胆酸钠
脱氧胆酸钠盐
脱氧胆酸钠直销
去氧胆酸钠(合成)
脱氧胆酸钠(进口)
脱氧胆酸钠(牛)标准品
| | 英文别名 | CCRIS 655
oxoniomethyl
OXIDE EXTRACT
UNII-436LS6U35Y
SODIUM CHOLEATE
Na-Desoxycholat
Sodium deoxycholate
Deoxycholate sodium
Sodium desoxycholate
Desoxycholate sodium
Sodium 7-deoxycholate
Sodium deoxycholic acid
Deoxycholic acid sodium
Na-Desoxycholat [German]
Deoxycholic acid sodium salt
Deoxycholic acid, sodium salt
Dihydroxy 3-12 cholanate de Na
SodiuM 3,12-dihydroxycholanate
Dihydroxy 3-12 cholanate de Na [French]
Sodium Deoxycholate [for Electrophoresis]
Natrium-3-alpha,12-alpha-dihydroxycholanat
sodium 3-α,12-α-dihydroxy-5-β-cholan-24-oate
sodium 3-α,12-α-dihydroxy-5-β-cholan-24-oate
Natrium-3-alpha,12-alpha-dihydroxycholanat [German]
Sodium 3-alpha,12-alpha-dihydroxy-5-beta-cholan-24-oate
sodium (3alpha,5beta,12alpha)-3,12-dihydroxycholan-24-oate
3-alpha,12-alpha-Dihydroxy-5-beta-cholan-24-oic acid sodium salt
cholan-24-oic acid, 3-hydroxy-, monosodium salt, (3alpha,5beta)-
5-beta-Cholan-24-oic acid, 3-alpha,12-alpha-dihydroxy-, sodium salt
Cholan-24-oic acid, 3,12-dihydroxy-, monosodium salt, (3alpha,5beta,12alpha)-
3,12-Dihydroxy-cholan-24-oic acid monosodium salt, (3-alpha,5-beta,12-alpha)- (9CI)
Cholan-24-oic acid, 3,12-dihydroxy-, monosodium salt, (3-alpha,5-beta,12-alpha)- (9CI)
| | CAS | 302-95-4
| | EINECS | 206-132-7 | | 化学式 | C24H41NaO4
| | 分子量 | 416.58 | | InChI | InChI=1/CO/c1-2/q+1 | | 密度 | 1.012 at 20.07℃ | | 熔点 | 357-365 °C | | 沸点 | 547.1 °C at 760 mmHg | | 比旋光度 | 44 º (c=2, H2O) | | 闪点 | >110°C (own results) | | 水溶性 | 330 g/L (15 ºC) | | 蒸汽压 | 0Pa at 20℃ | | 溶解度 | water: soluble1 gm in 10 ml, clear, colorless to very faintly yellow | | PH值 | 7.5-9.0 (20g/l, H2O, 20℃) | | 存储条件 | room temp | | 敏感性 | Easily absorbing moisture | | 外观 | Powder | | 颜色 | Yellow-tan | | 气味 | Odorless | | BRN | 3581950 | | MDL号 | MFCD00064139 | | 体外研究 | Deoxycholic acid (DCA) and chenoDeoxycholic acid (CDCA), as the common ingredients of duodenal reflux, act synergistically in many physiological and pathological processes. The cells are repeatedly exposed to 100 μM CDCA and Deoxycholic acid at pH 5.5 for up to 120 min. To simulate chronic local recurrent disease in vitro, the gastric cancer cell line MGC803 is exposed to acidified medium (pH 5.5) containing 100 μM Deoxycholic acid and CDCA. An untreated log-growth MGC803 cell line is generated to be used as a control in normal pH media. After daily 10 min exposure to the acidified bile acids for 60 weeks, MGC803-resistant cells are able to survive and proliferate after 120 min exposure. | | 危险品标志 | Xn - 有害物品
| | 风险术语 | R22 - 吞食有害。
R37 - 刺激呼吸系统。
| | 安全术语 | S22 - 切勿吸入粉尘。
S24/25 - 避免与皮肤和眼睛接触。
| | WGK Germany | 3 | | RTECS | FZ2250000 | | FLUKA BRAND F CODES | 3-10 | | TSCA | Yes | | 海关编号 | 29181930 | | 参考资料 展开查看 | 1. 姜越, 孙丹丹, 尹寿玉. 酮康唑固体脂质纳米粒的制备及质量评价[J]. 延边大学医学学报, 2016(04):30-33.
2. Yan, J., Hu, J., Yang, R. and Zhao, W. (2018), A new nanofibrillated and hydrophobic grafted dietary fibre derived from bamboo leaves: enhanced physicochemical properties and real adsorption capacity of oil. Int J Food Sci Technol, 53: 2394-2404. https://d
3. Yan, Jiai, et al. "Innovative nanofibrillated cellulose from rice straw as dietary fiber for enhanced health benefits prepared by a green and scale production method." ACS Sustainable Chemistry & Engineering 6.3 (2018): 3481-3492.https://doi.org/10.1021/ac
4. Kehao Huang, Bin Du, Baojun Xu,Alterations in physicochemical properties and bile acid binding capacities of dietary fibers upon ultrafine grinding,Powder Technology,Volume 326,2018,Pages 146-150,ISSN 0032-5910,https://doi.org/10.1016/j.powtec.2017.
5. Wang, Fangyuan, et al. "Facile nose-to-brain delivery of rotigotine-loaded polymer micelles thermosensitive hydrogels: In vitro characterization and in vivo behavior study." International journal of pharmaceutics 577 (2020): 119046.https://doi.org/10.1016/
6. [IF=8.198] Jiai Yan et al."Innovative Nanofibrillated Cellulose from Rice Straw as Dietary Fiber for Enhanced Health Benefits Prepared by a Green and Scale Production Method."Acs Sustain Chem Eng. 2018;6(3):3481–3492
7. [IF=6.475] Li Wang et al."Bilosomes as effective delivery systems to improve the gastrointestinal stability and bioavailability of epigallocatechin gallate (EGCG)."Food Res Int. 2021 Nov;149:110631
8. [IF=3.638] Xiangquan Zeng et al."In vitro studies on the interactions of blood lipid level-related biological molecules with gallic acid and tannic acid."J Sci Food Agr. 2019 Dec;99(15):6882-6892
9. [IF=1.902] Zhaohong Xi et al."Explore the effects of Shidan granules on chronic atrophic gastritis using LC–MS based plasma metabolomics study."Biomed Chromatogr. 2021 Sep;35(9):e5129 |
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