氯胺T钠 |
| 时间：2023-07-18 来源：化工号 作者：C7H11ClNNaO3S |
| 中文名 | 氯胺T钠
| | 英文名 | Chloramine-T sodium salt trihydrate
| | 别名 | 亚明T
氯胺T钠
三水合氯胺T
氯铵-T三水
氯胺T,三水
三水合氯铵-T
氯胺T三水合物
氯胺T钠三水合物
对甲苯磺酰氯胺钠盐
| | 英文别名 | CHLORAMINE T 3-HYDRATE
Chloroamine t trihydrate
Chloramine T sodium salt
Chloramine-T, Sodium salt
CHLORAMINE T REAGENT (ACS)
chloramine-t trihydrate, acs
Chloramine-T sodium salt trihydrate
N-Chloro-p-toluenesulfonamide, sodium salt
N-Chloro-p-toluenesulphonamide sodium salt trihydrate
N-Chloro-p-toluenesulfonamide sodium salt, Chloraminum
Benzenesulfonamide, N-chloro-4-methyl-, sodium salt, trihydrate
| | CAS | 7080-50-4
| | EINECS | 615-172-8 | | 化学式 | C7H11ClNNaO3S
| | 分子量 | 247.67 | | InChI | InChI=1/C7H8ClNO2S.Na.3H2O/c1-6-2-4-7(5-3-6)12(10,11)9-8;;;;/h2-5,9H,1H3;;3*1H2/q;+1;; | | 密度 | 1.43 | | 熔点 | 167-170°C(lit.) | | 闪点 | 92 °C | | 水溶性 | Soluble in water and ethyl alcohol. Insoluble in benzene and ethers. | | 溶解度 | H2O: passes test | | 酸度系数 | pK1:4.54(+1) (25°C) | | PH值 | 8-10 (50g/l, H2O, 20℃) | | 存储条件 | Store at +2°C to +8°C. | | 敏感性 | Moisture Sensitive | | 外观 | Crystalline Powder | | 颜色 | White to off-white | | 气味 | Chlorine like | | Merck | 14,2075 | | BRN | 3924168 | | 产品用途 | 防腐剂
| | MDL号 | MFCD00000522 | | 体外研究 | Gram-positive growth is reduced by 95% to 100% after tosylchloramide treatment, regardless of dose, with or without serum. E coli (gram-negative; with/without serum) is reduced 94% to 100% at antiseptic concentrations of 300 and 400 ppm. At 200 ppm, E coli growth is fully inhibited without serum present and by 50% with serum. At 100 and 200 ppm, cell viability remains greater than 90% under all experimental conditions. A 300-ppm, 3-minute exposure to tosylchloramide results in cell viability of up to 70%, with longer exposures producing lower viabilities. Serum does not affect cell viability in any condition. | | 体内研究 | A dose-dependently significant DNA damage in the rat tissues and inflammation is histopathologically noted around the terminal airways of the lung in both male and female rats. The 24-h exposure to 50 mg/L of chloramine-T is toxic for crayfish and leads to substantial loss of energy that became apparent during subsequently conducted physical stress. Tosylchloramide may potentiate the toxicity of many xenobiotics via metabolic activation and/or accumulation of reactive metabolites. The activities of CYP2E1, CYP1A1/2 CYP2B1/2, CYP3A4 and CYP4A1/2 enzymes significantly increase after treatment with 2.50, 5 and 10 mg/kg bw/day tosylchloramide, in a dose-dependent manner. This effect is not observed after tosylchloramide treatment at dose of 1.25 mg/kg bw/day. | | 危险品标志 | C - 腐蚀性物品
| | 风险术语 | R22 - 吞食有害。
R31 - 遇酸释放有毒气体。
R34 - 引起灼伤。
R42 - 吸入可能致敏。
| | 安全术语 | S22 - 切勿吸入粉尘。
S26 - 不慎与眼睛接触后，请立即用大量清水冲洗并征求医生意见。
S36/37/39 - 穿戴适当的防护服、手套和护目镜或面具。
S45 - 若发生事故或感不适，立即就医(可能的话，出示其标签)。
S7 - 保持容器密封。
| | 危险品运输编号 | UN 3263 8/PG 3 | | WGK Germany | 2 | | RTECS | XT5616800 | | TSCA | Yes | | 海关编号 | 29350090 | | Hazard Class | 8 | | Packing Group | III | | 下游产品 | 2-甲氧基-5-嘧啶硼酸 |
|
|
|
|
