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胆甾烯基豆蔻酸酯

时间:2023-07-18  来源:化工号   作者:C41H72O2
中文名 胆甾烯基豆蔻酸酯
英文名 Cholesteryl myristate
别名 胆甾醇豆蔻酸酯
胆固醇豆蔻酸酯
肉豆蔻酸胆固醇
豆蔻酸胆固醇酯
胆甾烯基豆蔻酸酯
肉豆蔻酸胆固醇酯
胆固醇肉豆蔻酸酯,液晶
英文别名 CM
Cholestryl myristate
Cholesteryl myristate
Cholesterol myristate
Cholesteryl Tetradecanoate
Cholest-5-en-3-yl myristate
MYRISTIC ACID CHOLESTEROL ESTER
cholest-5-en-3-yl tetradecanoate
3β-tetradecanoyloxycholest-5-ene
(3β)-cholest-5-en-3-yltetradecanoate
(3beta)-cholest-5-en-3-yl myristate
(3beta)-cholest-5-en-3-yl tetradecanoate
Cholest-5-en-3-ol (3beta)-, tetradecanoate
CAS 1989-52-2
EINECS 217-867-8
化学式 C41H72O2
分子量 597.01
InChI InChI=1/C41H72O2/c1-7-8-9-10-11-12-13-14-15-16-17-21-39(42)43-34-26-28-40(5)33(30-34)22-23-35-37-25-24-36(32(4)20-18-19-31(2)3)41(37,6)29-27-38(35)40/h22,31-32,34-38H,7-21,23-30H2,1-6H3
密度 0.9309 (rough estimate)
熔点 84 °C
沸点 589.77°C (rough estimate)
闪点 334.8°C
蒸汽压 8.15E-16mmHg at 25°C
溶解度 Chloroform (Slightly), Hexanes (Slightly)
折射率 1.5250 (estimate)
存储条件 Sealed in dry,2-8°C
外观 白色粉末
产品用途 本品仅供科研,不得用于其它用途。
体外研究 Mesenchymal stem cells (MSCs) transfected by the Id1 promoter reporter construct, cholesterol myristate increases the activity of Id1 promoter. Cholesterol myristate inhibits the apoptosis of MSCs induced by serum-free. Cholesterol myristate increases the expression of Id1 and its target gene bcl-x/l in MSCs treated with serum-free. Moreover, noggin, a BMP antagonist, reduces the anti-apoptotic effects of cholesterol myristate. Cholesterol myristate inhibits the apoptosis of PC12 cells induced in serum-free condition. Cholesterol myristate significantly increases the expression of BMP4, BMPRIA, p-Smad1/5/8, Id1 and its antiapoptotic target gene Bcl-xL in PC12 cells treated in serum-free condition.
危险品标志 Xi - 刺激性物品
刺激性物品
风险术语 36/37/38 - 刺激眼睛、呼吸系统和皮肤。
安全术语 S26 - 不慎与眼睛接触后,请立即用大量清水冲洗并征求医生意见。
S36 - 穿戴适当的防护服。
WGK Germany 3
参考资料 展开查看 1. Song, Z., Lu, Y., Zhang, X., Wang, H., Han, J., & Dong, C. (2016). Novel curcumin-loaded human serum albumin nanoparticles surface functionalized with folate: characterization and in vitro/vivo evaluation. Drug design, development and therapy, 10, 2643–264
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