MELEAGRIN |
| 时间：2023-07-15 来源：化工号 作者：C23H23N5O4 |
| 中文名 | MELEAGRIN
| | 英文名 | MELEAGRIN
| | 别名 | 化合物 T16035
| | 英文别名 | MELEAGRIN
Meleagrine
6-O-Methyloxaline, Meleagrine
| | CAS | 71751-77-4
| | EINECS | 604-604-1 | | 化学式 | C23H23N5O4
| | 分子量 | 433.46 | | 熔点 | >165oC | | 溶解度 | Soluble in DMSO (up to 10 mg/ml) | | 存储条件 | -20°C | | 稳定性 | Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months. | | 外观 | Yellow oil. | | 颜色 | Tan | | 体外研究 | Meleagrin inhibits the growth of the human breast cancer cell lines MDA-MB-231, MDA-468, BT-474, SK BR-3, MCF7 and MCF7-dox. Meleagrin causes a dose-dependent inhibition of HGF-induced cell migration, and invasion of breast cancer cell lines. | | 体内研究 | Meleagrin potently suppresses the invasive triple negative breast tumor cell growth in an orthotopic athymic nude mice model. |
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