23513-14-6 |
| 时间：2023-07-15 来源：化工号 作者：C17H26O4 |
| 中文名 | 6-姜酚
| | 英文名 | 6-Gingerol
| | 别名 | 6-姜酚
没食子酚儿茶素
6-姜酚, 来源于生姜
6-GINGEROL 6-姜酚
6-姜辣素,姜酮醇,没食子酚儿茶素
6-姜酚(6-姜辣素,姜酮醇,没食子酚儿茶素
5-羟基-1-(4-羟基-3-甲氧基苯基)-3-癸酮
(5S)-5-羟基-1-(4-羟基-3-甲氧基苯基)癸-3-酮
| | 英文别名 | GINGEROL
6-Gingerol
6-GINGEROL
GINGEROL [6]
[6]-GINGEROL, ZINGIBER OFFICINALE
5-hydroxy-1-(4-hydroxy-3-methoxyphenyl)decan-3-one
5-HYDROXY-1-(4'-HYDROXY-3'-METHOXYPHENYL)-3-DECANONE
1-(4'-HYDROXY-3'-METHOXYPHENYL)-5-HYDROXY-3-DECANONE
(S)-5-HYDROXY-1-(4-HYDROXY-3-METHOXY-PHENYL-3-DECANONE
(S)-5-Hydroxy-1-(4-hydroxy-3-methoxy-phenyl-3-decanone
(5S)-5-hydroxy-1-(4-hydroxy-3-methoxyphenyl)decan-3-one
(5s)-5-hydroxy-1-(4-hydroxy-3-methoxy-phenyl)decan-3-one
| | CAS | 23513-14-6
| | EINECS | 607-241-6 | | 化学式 | C17H26O4
| | 分子量 | 294.39 | | InChI | InChI=1/C17H26O4/c1-3-4-5-6-14(18)12-15(19)9-7-13-8-10-16(20)17(11-13)21-2/h8,10-11,14,18,20H,3-7,9,12H2,1-2H3/t14-/m0/s1 | | InChIKey | NLDDIKRKFXEWBK-AWEZNQCLSA-N | | 密度 | 1.083±0.06 g/cm3(Predicted) | | 熔点 | 31℃ | | 沸点 | 453.0±35.0 °C(Predicted) | | 比旋光度 | +26.5 (c, 1 in CHCl3) | | 闪点 | 159°C | | 蒸汽压 | 5.39E-09mmHg at 25°C | | 溶解度 | methanol: soluble1mg/mL, clear, colorless | | 折射率 | 1.522 | | 酸度系数 | 10.02±0.20(Predicted) | | 存储条件 | -20°C | | 敏感性 | Sensitive to light | | 外观 | Pale yellow oil | | 颜色 | White to Light yellow | | 物化性质 | 白色蜡状固体，可溶于甲醇、乙醇、DMSO等有机溶剂，来源于干姜、生姜，郁金。 | | MDL号 | MFCD00210507 | | 危险品标志 | Xn - 有害物品
| | 风险术语 | R22 - 吞食有害。
R36/37/38 - 刺激眼睛、呼吸系统和皮肤。
| | 安全术语 | S26 - 不慎与眼睛接触后，请立即用大量清水冲洗并征求医生意见。
S36/37 - 穿戴适当的防护服和手套。
| | 危险品运输编号 | UN 2811 6.1 / PGIII | | WGK Germany | 3 | | RTECS | HE0757000 | | 海关编号 | 29145090 | | 参考资料 展开查看 | 1. 李敏 刘元涛 王垒 王升光 张惠惠 邵珠德 代龙 高鹏. 不同温胆汤制剂中6-姜辣素的含量对比研究[J]. 时珍国医国药(8期):1901-1903.
2. 周泉, 王晗雪, 李素丽,等. 舒心通脉颗粒提取工艺的优化[J]. 中成药, 2019(10).
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4. 梁娜 桑亚新 周妍 刘卫华 李田叶 王向红.HPLC-ESI-Q-TOF-MS/MS法分析干姜中的姜辣素类化合物[J].食品工业科技 2018 39(09):252-256.
5. 王志荣, 黎志立, 李明艳,等. 福建鲜姜,干姜中主要成分比较.
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10. 邵珠莹,潘金火,张月婵,蒋志涛,王雪,冯星月,王建春.6-姜酚对马兜铃酸A诱导的HK-2肾小管上皮细胞损伤的保护作用[J].中成药,2020,42(10):2744-2747.
11. 莉莉,陈勇,张蒙伟,鄢红霞,高守红,陈万生.UHPLC-MS/MS法测定新冠肺炎经验方寒湿郁肺汤中11种主成分的含量[J].药学实践杂志,2021,39(02):148-151+156.
12. 王志荣,黎志立,李明艳,高紫丹,王宝华,李长红,李文旭.福建鲜姜、干姜中主要成分比较[J].中成药,2020,42(08):2230-2236.
13. 刘加瑶,贺怡,田金洁,王利胜,谢波,凌家俊.四逆汤活性成分在血液和心脏部位微透析方法的建立[J].中药新药与临床药理,2020,31(09):1086-1091.
14. 兰济乐,阮叶萍,邱璐琦.基于BAS-GA-BP神经网络结合熵权法多指标优化风引汤提取工艺[J].中国中药杂志,2020,45(23):5686-5693.
15. Arshad Zahoor, Chao Yang, Yaping Yang, Yingfang Guo, Tao Zhang, Kangfeng Jiang, Shuai Guo, Ganzhen Deng, 6-Gingerol exerts anti-inflammatory effects and protective properties on LTA-induced mastitis, Phytomedicine, Volume 76, 2020, 153248, ISSN 0944-7113,
16. [IF=2.863] Xue Han et al."6-Gingerol, an active pungent component of ginger, inhibits L-type Ca2+ current, contractility, and Ca2+ transients in isolated rat ventricular myocytes."Food Sci Nutr. 2019 Apr;7(4):1344-1352
17. [IF=11.878] Li Xinming et al."A fast and specific fluorescent probe for thioredoxin reductase that works via disulphide bond cleavage."Nat Commun. 2019 Jun;10(1):1-12
18. [IF=5.81] Cui Lihua et al."Chaihu Guizhi Ganjiang Decoction Ameliorates Pancreatic Fibrosis via JNK/mTOR Signaling Pathway."Front Pharmacol. 2021 Jun;0:1369
19. [IF=5.396] Xie Xing et al."Influence of Sargassum pallidum and the synergistic interaction mechanism of 6-gingerol and poricoic acid A on inhibiting ovalbumin glycation."Food Funct. 2021 Oct;12(19):9315-9326
20. [IF=4.268] Arshad Zahoor et al."6-Gingerol exerts anti-inflammatory effects and protective properties on LTA-induced mastitis."Phytomedicine. 2020 Sep;76:153248
21. [IF=0.986] Ji-le Lan et al."Q-marker Prediction Analysis of Rhubarb in Fengyin Decoction Based on Fingerprint and Network Pharmacology:."Nat Prod Commun. 2021;16(8):
22. [IF=6.048] Xue Han et al."6-Gingerol exerts a protective effect against hypoxic injury through the p38/Nrf2/HO-1 and p38/NF-κB pathway in H9c2 cells."J Nutr Biochem. 2022 Mar;:108975
23. [IF=6.529] Zhe Cheng et al."6-gingerol ameliorates metabolic disorders by inhibiting hypertrophy and hyperplasia of adipocytes in high-fat-diet induced obese mice."Biomed Pharmacother. 2022 Feb;146:112491
24. [IF=3.765] Liu Miaomaio et al."Inhibition of human ether-à-go-go-related gene K+ currents expressed in HEK293 cells by three gingerol components from ginger."JOURNAL OF PHARMACY AND PHARMACOLOGY. 2022 May;: |
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