2646-71-1 |
时间:2023-07-15 来源:化工号 作者:C21H31N7NaO17P3 |
中文名 | 还原型辅酶Ⅱ四钠
| 英文名 | Dihydronicotinamide-adenine dinucleotide phosphate, tetrasodium salt
| 别名 | 还原型辅酶Ⅱ四钠 还原型辅酶II四钠 NADPH 还原型辅酶Ⅱ四钠 还原型辅酶Ⅱ四钠盐(+4°C) 还原型辅酶四钠盐(-20`C) 还原辅酶Ⅱ四钠盐(Β-NADPH) 还原辅酶Ⅱ四钠盐(Β-NADPH.4NA) Β-烟酰胺腺嘌呤二核苷酸磷酸四钠盐, 还原型 Β-烟碱腺嘌呤二核苷磷酸盐四钠盐, 还原型[生物化学用]
| 英文别名 | BETA-NADPH Beta-Nadph Tetrasodium Salt TRIPHOSPHOPYRIDINE NUCLEOTIDE, REDUCED FORM, TETRASODIUM BETA-TRIPHOSPHOPYRIDINE NUCLEOTIDE, SODIUM, REDUCED FORM TRIPHOSPYRIDINE NUCLEOTIDE, REDUCED FORM TETRASODIUM SALT TRIPHOSPHOPYRIDINE NUCLEOTIDE, REDUCED FORM TETRASODIUM SALT dihydronicotinamide-adenine dinucleotide phosphate tetrasodium BETA-TRIPHOSPHOPYRIDINE NUCLEOTIDE TETRASODIUM SALT,REDUCED FORM Dihydronicotinamide Adenine Dinucleotide Pphosphate Tetrasodium Salt Dihydronicotinamide-adenine dinucleotide phosphate, tetrasodium salt [(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-3-hydroxy-4-phosphonooxy-tetrahydrofuran-2-yl]methyl [[(2R,3S,4R,5R)-5-(3-carbamoyl-4H-pyridin-1-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl] hydrogen phosphate tetrasodium [(2R,3S,4R,5R)-2-(6-aminopurin-9-yl)-5-[[[[(2R,3R,4S,5S)-5-(3-carbamoyl-4H-pyridin-1-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-oxido-phosphoryl]oxy-oxido-phosphoryl]oxymethyl]-4-hydroxy-tetrahydrofuran-3-yl] phosphate
| CAS | 2646-71-1
| EINECS | 220-163-3 | 化学式 | C21H31N7NaO17P3
| 分子量 | 769.42 | InChI | InChI=1/C21H30N7O17P3.4Na/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(44-46(33,34)35)14(30)11(43-21)6-41-48(38,39)45-47(36,37)40-5-10-13(29)15(31)20(42-10)27-3-1-2-9(4-27)18(23)32;;;;/h1,3-4,7-8,10-11,13-16,20-21,29-31H,2,5-6H2,(H2,23,32)(H,36,37)(H,38,39)(H2,22,24,25)(H2,33,34,35);;;;/q;4*+1/p-4/t10-,11-,13+,14-,15+,16+,20+,21-;;;;/m1..../s1 | 熔点 | >250°C (dec.) | 水溶性 | Soluble in water (50 mg/ml). | 溶解度 | 10 mM NaOH: soluble50mg/mL, clear | 存储条件 | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C | 敏感性 | Light Sensitive | 外观 | Powder | 颜色 | White to Off-white | Merck | 14,6348 | 产品用途 | 本品仅供科研,不得用于其它用途。 | MDL号 | MFCD00057028 | 危险品标志 | Xi - 刺激性物品
F - 易燃物品
| 风险术语 | R36/37/38 - 刺激眼睛、呼吸系统和皮肤。
R11 - 高度易燃。
| 安全术语 | S26 - 不慎与眼睛接触后,请立即用大量清水冲洗并征求医生意见。
S36/37 - 穿戴适当的防护服和手套。
| WGK Germany | 3 | FLUKA BRAND F CODES | 3-10-23 | 海关编号 | 29349990 | 参考资料 展开查看 | 1. 陈荣达 谢静 史玉蕊 刘桂明 郑梅竹 李丽.CYP3A4酶对土茯苓黄酮类成分代谢的影响[J].分析试验室 2020 39(07):760-765. 2. 张松 李啸 石小丹 等. 产酮基还原酶基因工程菌培养温度和转速条件的优化[J]. 中国酿造 2016 35(02):85-89. 3. 朱利娟 余涛 顾颖 等. 双酶体系高效制备(R)-2-氯-1-(3-氯苯基)乙醇[J]. 食品与生物技术学报 2016 35(03):278-283. 4. 石小丹 李啸 罗宇笛 等. 发酵液中酮基还原酶活性测定方法的构建[J]. 中国酿造 2014 33(009):151-155. 5. 朱利娟, 胡蝶, 储亚琴,等. 多酶偶联催化制备手性化合物(S)-环氧苯乙烷[J]. 食品与生物技术学报, 2017, 36(5):473-478. 6. 周国坚,叶董婷,邓旭杏.板蓝根颗粒、茵栀黄颗粒和复方黄连素片对药物代谢酶CYP_3A_4活性的影响[J].中医药导报,2017,23(03):72-74. 7. 王杰, 王笃军, 李凤伟,等. 海蓬子发芽富集γ-氨基丁酸和黄酮类化合物的条件优化及关键酶活性的研究[J]. 食品研究与开发, 2019, v.40;No.372(23):66-73. 8. 余涛, 胡蝶, 邬敏辰,等. 重组葡萄糖脱氢酶的酶学性质及其偶联辅酶再生[J]. 食品与生物技术学报, 2014, 033(009):910-916. 9. 王伟 李官平 张玉 等. 利用HPLC法检测活性肽HMG-CoA还原酶抑制剂活性[J]. 浙江农业学报 2015 027(004):652-656. 10. Wang, Xiaohong, and Wanzhong Li. "Antioxidantactivity of polyphenols from Toona sinensis roem seeds and the inhibition of aldose reductase." African Journal of Traditional, Complementary and Alternative Medicines 13.1 (2016): 99-104.10.4314/ajtcam.v13i1.14 11. [IF=2.112] Yu Tao et al."Reduction of m-chlorophenacyl chloride coupled with regeneration of NADPH by recombinant Escherichia coli cells co-expressing both carbonyl reductase and glucose 1-dehydrogenase."Ann Microbiol. 2016 Mar;66(1):343-350 12. [IF=11.413] Yan Yin et al."De novo biosynthesis of liquiritin in Saccharomyces cerevisiae."Acta Pharm Sin B. 2020 Apr;10:711 13. [IF=4.155] Siqi Zhang et al."Step-wise immobilization of multi-enzymes by zirconium-based coordination polymer in situ self-assembly and specific absorption."J Inorg Biochem. 2020 Jul;208:111093 14. [IF=3.5] Yue Li et al."Clarify the potential cholestatic hepatotoxicity components from Chinese Herb Medicine and metabolism’s role via hBSEP vesicles and S9/hBSEP vesicles."Toxicol In Vitro. 2022 Apr;80:105324 15. [IF=5.279] Chenggang Song et al."Bioactive Monomer and Polymer Polyketides from Edible Mushroom Cortinarius caerulescens as Glutamate Dehydrogenase Inhibitors and Antioxidants."J Agr Food Chem. 2022;XXXX(XXX):XXX-XXX |
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