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78821-43-9

时间:2023-07-15  来源:化工号   作者:C28H48O6
  • 天丰素
  • 油菜素内酯
  • 八仙丰产素
  • 欧洲油菜素
  • 芸苔素内酯
  • 布拉西诺内酯
  • 表油菜素内酯
  • 24-表芸苔素内酯
  • BRASSINOLIDE 24-表油菜素内酯
  • (22R,23R,24R)-2Α,3Α,22,23-四羟基-24-甲基-5Α-胆甾-6-酮
  • (22R,23R,24R)-2Α,3Α,22,23-四羟基-Β-高-7-氧杂-5Α-麦角甾-6-酮
  • (22R,23R,24R)-2α,3α,22,23-四羟基-24-甲基-β-均-7-氧杂-5-胆甾-6-酮
  • 中文名 天丰素
    英文名 epibrassinolide
    别名 天丰素
    油菜素内酯
    八仙丰产素
    欧洲油菜素
    芸苔素内酯
    布拉西诺内酯
    表油菜素内酯
    24-表芸苔素内酯
    BRASSINOLIDE 24-表油菜素内酯
    (22R,23R,24R)-2Α,3Α,22,23-四羟基-24-甲基-5Α-胆甾-6-酮
    (22R,23R,24R)-2Α,3Α,22,23-四羟基-Β-高-7-氧杂-5Α-麦角甾-6-酮
    (22R,23R,24R)-2α,3α,22,23-四羟基-24-甲基-β-均-7-氧杂-5-胆甾-6-酮
    英文别名 BP55
    B1105
    CS-1258
    Brassinolide
    epibrassinolide
    24R-BRASSINOLIDE
    24-Epibrassinolide
    24-EPIBRASSINOLIDE
    22R,23R,24R-2A,3A,22,23-TETRAHYDROXY-B-HOMO-7-OXA-5A-ERGOSTAN-6-ONE
    22R,23R,24R-2ALPHA,3ALPHA,22,28-TETRAHYDROXY-B-HOMO-7-OXA-5ALPHA-ERGOSTA-6-ONE
    (22R,23R,24R)-2-ALPHA,3-ALPHA,22,23-TETRAHYDROXY-24-METHYL-B-HOMO-7-OXA-5-ALPHA-CHOLESTAN-6-ONE
    (3aS,5S,6R,7aR,7bS,9aS,12aS,12bS)-10-[(1S,2S,3R,4R)-2,3-dihydroxy-1,4,5-trimethylhexyl]-5,6-dihydroxy-7a,9a-dimethylhexadecahydro-3H-benzo[c]indeno[5,4-e]oxepin-3-one
    (3aS,5S,6R,7aR,7bS,9aS,10R,12aS,12bS)-10-[(2S,3R,4R,5R)-3,4-dihydroxy-5,6-dimethylheptan-2-yl]-5,6-dihydroxy-7a,9a-dimethylhexadecahydro-3H-benzo[c]indeno[5,4-e]oxepin-3-one
    (3aS,5S,6R,7aR,7bS,9aS,10R,12aS,12bS)-10-[(2S,3R,4R,5S)-3,4-dihydroxy-5,6-dimethylheptan-2-yl]-5,6-dihydroxy-7a,9a-dimethylhexadecahydro-3H-benzo[c]indeno[5,4-e]oxepin-3-one
    CAS 78821-43-9
    72962-43-7
    EINECS 639-387-1
    化学式 C28H48O6
    分子量 480.68
    InChI InChI=1/C28H48O6/c1-14(2)15(3)24(31)25(32)16(4)18-7-8-19-17-13-34-26(33)21-11-22(29)23(30)12-28(21,6)20(17)9-10-27(18,19)5/h14-25,29-32H,7-13H2,1-6H3/t15-,16+,17+,18?,19+,20+,21-,22+,23-,24-,25+,27-,28-/m1/s1
    密度 1.141±0.06 g/cm3(Predicted)
    熔点 256°C
    沸点 633.7±55.0 °C(Predicted)
    比旋光度 D27 +16°
    闪点 202.3°C
    蒸汽压 1.01E-18mmHg at 25°C
    溶解度 Chloroform (Slightly), Ethyl Acetate (Slightly)
    折射率 1.535
    酸度系数 14.27±0.70(Predicted)
    存储条件 -20°C
    外观 Solid
    颜色 White to Off-White
    物化性质 白色晶体粉末
    产品用途 属广谱性高效植物生长调节剂,对各种经济作物均有明显增产作用,能有效调节植物各个生长环节
    MDL号 MFCD00133310
    体外研究 Epibrassinolide (EBR) is a biologically active compound of the brassinosteroids, steroid-derived plant growth regulator family. Cells are incubated with various doses (0-100 μM) of Epibrassinolide for 24 or 48 h and cell viability is determined by MTT assay. Epibrassinolide induced cell viability loss in dose- and time-dependent manner compared to untreated samples in LNCaP and DU145 prostate cancer cells. Increasing concentrations of Epibrassinolide is more effective on LNCaP cell viability loss than DU145 cells suggesting that androgen-dependent cells are more sensitive to Epibrassinolide than androgen-independent prostate cancer cells. In further experiments, 25 μM Epibrassinolide is selected due to its moderate cytotoxic effect on both cell lines. The effect of Epibrassinolide treatment is examined on cell proliferation by counting the cell number within 96 h. A higher and earlier inhibition of cell proliferation is observed in LNCaP than DU145 cells.
    风险术语 R22 - 吞食有害。
    R36/37/38 - 刺激眼睛、呼吸系统和皮肤。
    安全术语 S22 - 切勿吸入粉尘。
    S36/37/39 - 穿戴适当的防护服、手套和护目镜或面具。
    S45 - 若发生事故或感不适,立即就医(可能的话,出示其标签)。
    WGK Germany 3
    海关编号 29372900
    参考资料 展开查看 1. 叶青雷 李志 王立志 张跃辉 张静 孙晓东.不同外源激素对桑树种子发芽的影响[J].黑龙江农业科学 2015(11):78-80.
    2. 郭淑华 张淑辉 刘佰霖 刘笑宏 杜远鹏.不同植物生长调节剂组合对夏黑葡萄品质的影响[J].落叶果树 2016 48(04):6-9.
    3. 高邦年. 油菜素内酯对普通油茶春梢和茶籽相关指标的影响[J]. 安徽农业科学, v.42;No.434(01):132-134.
    4. 吴进东. 油菜素内酯对霍山石斛抗冷性能的调控效应[J]. 西北植物学报, 2015(05):985-990.
    5. 李硕, 张毅, 姚棋,等. 等渗盐胁迫下BR对番茄生长及渗透调节特性的影响[J]. 西北农林科技大学学报(自然科学版), 2020, 048(004):130-136,145.
    6. 郑立伟, 马娟娟, 张东,等. 苹果矮化砧木T337 MdCBB1基因的克隆与表达分析[J]. 西北农业学报, 2016, 25(9):1365-1370.
    7. [IF=4.183] Yukun Chen et al."Seed-Specific Gene MOTHER of FT and TFL1 (MFT) Involved in Embryogenesis, Hormones and Stress Responses in Dimocarpus longan Lour.."Int J Mol Sci. 2018 Aug;19(8):2403
    8. [IF=5.279] Shenghuai Hou et al."Boronic Acid-Functionalized Scholl-Coupling Mesoporous Polymers for Online Solid-Phase Extraction of Brassinosteroids from Plant-Derived Foodstuffs."J Agr Food Chem. 2021;69(16):4883–4893
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