三(2-甲酰乙基)膦盐酸盐 |
| 时间：2023-07-18 来源：化工号 作者：C9H16ClO6P |
| 中文名 | 三(2-甲酰乙基)膦盐酸盐
| | 英文名 | Tris-(2-carboxyethyl)-phosphine hydrochloride
| | 别名 | TCEP盐酸盐
三(2-羧乙基)膦盐酸盐
三(2-羧乙基)磷盐酸盐
三(2-酰乙基)磷盐酸盐
三(2-甲酰乙基)膦盐酸盐
三(2-羰基乙基)磷盐酸盐
(TCEP盐酸盐) 三(2-甲酰乙基)膦盐酸盐
三(2-羰基乙基)磷盐酸盐(TCEP.HCL )
| | 英文别名 | 500 MM TCEP
TCEP-HCl, OMniPur(R)
Tris(carboxyethyl)phosphine.HC
3,3',3''-phosphanetriyltripropanoate
Tris(2-carboxyethyl)phosphine hydrochloride
Tris-(2-carboxyethyl)-phosphine hydrochloride
3,3',3''-phosphanetriyltripropanoic acid hydrochloride
Tris(2-carboxyethyl)phosphine hydrochloride solution,TCEP
Tris(2-carboxyethyl)phosphine hydrochloride, 0.5M soln in water
| | CAS | 51805-45-9
| | EINECS | 629-759-1 | | 化学式 | C9H16ClO6P
| | 分子量 | 286.65 | | InChI | InChI=1/C9H15O6P/c10-7(11)1-4-16(5-2-8(12)13)6-3-9(14)15/h1-6H2,(H,10,11)(H,12,13)(H,14,15)/p-3 | | InChIKey | PBVAJRFEEOIAGW-UHFFFAOYSA-N | | 密度 | 1.041g/mLat 25°C | | 熔点 | 177 °C | | 沸点 | 519.4°C at 760 mmHg | | 闪点 | 267.9°C | | 水溶性 | Soluble in water and methanol. | | 蒸汽压 | 3.51E-12mmHg at 25°C | | 溶解度 | H2O: 50mg/mL | | 折射率 | n20/D 1.367 | | 酸度系数 | 7.66(at 25℃) | | PH值 | 7.0(aqueous solution; pH was adjusted with ammonium hydroxide) | | 存储条件 | 2-8°C | | 稳定性 | Stable for 1 year from date of purchase as supplied. Solutions in distilled water may be stored at -20°C for up to 1 month. | | 敏感性 | Moisture Sensitive | | 外观 | powder | | 颜色 | white | | 最大波长(λmax) | ['λ: 260 nm Amax: 0.05',
, 'λ: 280 nm Amax: 0.03'] | | Merck | 14,9085 | | BRN | 3724376 | | MDL号 | MFCD00145469 | | 体外研究 | TCEP hydrochloride has been introduced which oers the prospect of serving as an alternative to the more commonly employed DTT in the NF-κB-DNA binding reactions in vitro, using recombinant p50 protein and a 32 P-labelled κB oligonucleotide. DTT promotes NF-κB-DNA binding in concentrations from 0.25 to 2.6 mM in binding reactions. However, in the presence of 0.25 mM DTT, inhibition of NF-κB binding is seen only at Hg 2+ concentrations greater than 100 μM and results are highly variable. In contrast, TCEP hydrochloride promotes NF-κB-DNA binding in a dose-related manner in concentrations from 0.25 to 6 mM. In the presence of even 6 mM TCEP hydrochloride, Hg 2+ prevents NF-κB-DNA binding at concentrations as low as 20 μM in binding reactions. The human lactoferrin (hLF) peptide is dissolved in phosphate buffer to a concentration of 0.1 mm. Reduction of the disulfide bonds is obtained by adding a 30-fold molar excess of TCEP hydrochloride with subsequent incubation for 2 h at 37 ℃. | | 危险品标志 | C - 腐蚀性物品
Xi - 刺激性物品
| | 风险术语 | R36/38 - 刺激眼睛和皮肤。
R36/37/38 - 刺激眼睛、呼吸系统和皮肤。
R34 - 引起灼伤。
| | 安全术语 | S26 - 不慎与眼睛接触后，请立即用大量清水冲洗并征求医生意见。
S37/39 - 戴适当的手套和护目镜或面具。
S36/37/39 - 穿戴适当的防护服、手套和护目镜或面具。
S27 - 一旦衣物受到污染，请立即脱去。
S45 - 若发生事故或感不适，立即就医(可能的话，出示其标签)。
| | 危险品运输编号 | UN 3261 8/PG 2 | | WGK Germany | 2 | | FLUKA BRAND F CODES | 10 | | TSCA | No | | 海关编号 | 29319090 | | Hazard Class | 8 | | Packing Group | III | | 参考资料 展开查看 | 1. Cheng, Zhongzhe, et al. "Determination of thailandepsin B in rat plasma with a LC–MS/MS method." Bioanalysis 7.1 (2015): 39-52.36.161.84.113
2. Baoshan He, Xiaoze Dong, Nb.BbvCI powered DNA walking machine-based Zr-MOFs-labeled electrochemical aptasensor using Pt@AuNRs/Fe-MOFs/PEI-rGO as electrode modification material for patulin detection, Chemical Engineering Journal, Volume 405, 2021, 126642,
3. [IF=13.273] Baoshan He et al."Nb.BbvCI powered DNA walking machine-based Zr-MOFs-labeled electrochemical aptasensor using Pt@AuNRs/Fe-MOFs/PEI-rGO as electrode modification material for patulin detection."Chem Eng J. 2021 Feb;405:126642
4. [IF=10.588] Yuanyuan Liu et al."A magnetic relaxation switching and visual dual-mode sensor for selective detection of Hg2+ based on aptamers modified Au@Fe3O4 nanoparticles."J Hazard Mater. 2020 Apr;388:121728
5. [IF=7.46] Min Wei et al."Development of the signal amplification based on Au@Pt/MIL-101(Cr) as mimetic enzyme and RecJf exonuclease-assistant target recycling."Sensor Actuat B-Chem. 2020 Jun;312:128019
6. [IF=3.361] Huali Jin et al."An electrochemical aptasensor for lead ion detection based on catalytic hairpin assembly and porous carbon supported platinum as signal amplification."Rsc Adv. 2020 Feb;10(11):6647-6653
7. [IF=3.223] Min Wei et al."Electrochemical Aptasensor for Zearalenone Based on DNA Assembly and Exonuclease III as Amplification Strategy."Electroanal. 2021 Jul;33(7):1691-1698
8. [IF=1.967] Chenling Qu et al."A homogeneous electrochemical aptasensor based on DNA assembly for zearalenone detection."J Chin Chem Soc-Taip. 2021 Oct;68(10):1998-2005
9. [IF=4.464] Lina Lv et al."A “signal off” aptasensor based on AuNPs/Ni-MOF substrate-free catalyzed for detection Enrofloxacin."J Electroanal Chem. 2022 Apr;911:116251
10. [IF=9.229] Miaomiao Han et al."Amyloid Protein-Biofunctionalized Polydopamine Nanoparticles Demonstrate Minimal Plasma Protein Fouling and Efficient Photothermal Therapy."Acs Appl Mater Inter. 2022;XXXX(XXX):XXX-XXX
11. [IF=14.188] Xuehui Liu et al."Stimuli-Mediated Specific Isolation of Exosomes from Blood Plasma for High-Throughput Profiling of Cancer Biomarkers."Small Methods. 2021 Dec 19
12. [IF=13.273] Yuan Li et al."Biocatalytic living materials built by compartmentalized microorganisms in annealable granular hydrogels."CHEMICAL ENGINEERING JOURNAL. 2022 Oct;445:136822
13. [IF=3.223] Zeping Lv et al."An ultrasensitive DNA sensor for Hg2+ assay based on electrodeposited Au/carbon nanofibers-chitosan and reduced graphene oxide."ELECTROANALYSIS |
|
|
|
|
